Pyridoxal 5’-phosphate is the coenzyme form of B6; methylcobalamin is the methylated form of B12; L-methylfolate is the form of folate the body uses directly. Cheaper complexes use pyridoxine, cyanocobalamin and folic acid, which have to be converted first. All three of ours are named on the ingredient list — you can check.

Per capsule, from the label: thiamine 50 mg, riboflavin 40 mg, niacin 50 mg, pantothenic acid 50 mg, vitamin B6 8.4 mg, biotin 500 µg, folate 400 µg and vitamin B12 100 µg. Every one of the eight is at 200% of its reference value or more. Beside them: betaine 100 mg, and choline, inositol and PABA at 25 mg each.

Between them, the B vitamins contribute to normal energy-yielding metabolism, to the reduction of tiredness and fatigue, to the normal functioning of the nervous system and to normal psychological function. Each of those belongs to particular vitamins of the eight, not to the capsule as a whole.

Riboflavin. It is water-soluble, you excrete what you do not use, and it is a strong yellow pigment. It is harmless and it is the single most common question about any B-complex.

One capsule in the first half of the day, after food. B vitamins are involved in energy metabolism and some people find a late dose unhelpful for sleep.

Yes. The capsule shell is HPMC and the B12 is methylcobalamin, which is produced by fermentation rather than from an animal source.

The label advises against use by anyone pregnant or breastfeeding and by anyone under 18. If you take medication — levodopa in particular interacts with B6 — speak to your pharmacist first.